为评估高剂量达托霉素用于肥胖患者的安全性及风险因素，研究发现肥胖患者风险更高，或可调整剂量。 肥胖患者使用 4mg/kg 达托霉素治疗时，药物暴露会增加 30%，这可能会提高诸如横纹肌溶解等不良事件（AEs）的发生风险。鉴于在这一人群中使用更高剂量 ...

Background: This subgroup analysis of the European Cubicin Outcomes Registry Experience evaluated the safety and effectiveness of daptomycin in children and adolescent patients (<18 years).

The aim of this study was to evaluate the effectiveness of daptomycin in the treatment of patients with vancomycin-resistant enterococcal urinary tract infection treated in our 200-bed community ...

One of these, daptomycin, also belongs to the lipopeptide class of antibiotics. In a paper published in Microbiology Spectrum recently, Dr Tanya Decker (neé Clements) from Stellenbosch University ...