Epidermal hyperplasia is a key feature of the common skin disorder psoriasis. Stimulation of epidermal keratinocytes by insulin-like growth factor I (IGF-I) is essential for cell division ...

The T-cell-derived cytokine interleukin (IL)-21 has a key role in the process of epidermal hyperplasia in psoriasis, and blocking this cytokine might be an effective therapy for patients with this ...