Perhaps a grand unified theory will emerge whereby the three fundamental forces in schizophrenia research (NMDA, GABA and dopamine) all become united by the involvement of reactive oxygen species ...

Instead, researchers turned to an idea called the dopamine hypothesis, which argued that schizophrenia was a result of an imbalance or dysregulation in the way dopamine was transmitted ...

Two main theories have emerged: the "synergy hypothesis," which suggests dopamine handles short-term rewards while serotonin manages long-term benefits, and the "opponency hypothesis," which ...