show that phase separation of the FOXM1 transcription factor is important for its oncogenic function and is inhibited by AMP-activated protein kinase ... is driven by dynamic, weak multivalent ...
It has recently been reported that the phase separation associated with ferroptosis suppressing protein 1 (FSP1) can be used in an effective therapeutic intervention against cancer. "Liquid-liquid ...
“I was pretty confident that the protein would undergo phase separation, but we were in for big surprises,” said Deshpande. On evaporating a droplet with high concentration of GRP77, he saw gel-like ...