One of the striking features of this model is its asymmetric structure in which ... this cavity could accommodate ubiquitin-charged ubiquitin conjugating (E2) enzymes and known APC substrates ...

SignalChem Biotech supports research into new PROTAC®-based therapies by offering a diverse array of ubiquitin enzymes, including CRBN/DDB1/Cul4A/Rbx1 complexes, E1 activating enzymes, E2 conjugating ...