研究结果如下： 两样本 MR 分析：对 5 种与 EBV 感染相关的抗体（AEB-IgG、EA-D、EBNA-1、VCA-p18、ZEBRA）与 BCa 进行分析，发现 EBNA-1（OR =1.15，95% CI：1.01 - 1.30；p =0.039）和 VCA-p18（OR=1.36，95% CI：1.13 - 1.64；p =0.001）可能增加 BCa 风险，经 FDR 校正后，只有 ...

在实验技术方面，研究人员主要运用了以下几种关键技术：首先是 DNA 提取技术，他们采用特定试剂盒从石蜡包埋组织中提取 DNA，并使用分光光度计检测其质量；接着是实时荧光定量 PCR（Real-time PCR）技术，通过该技术检测 HPV-16 的 E2 和 E6 基因、EBV 的 EBNA-1 基因 ...

Increased EBV antibody levels have previously been reported ... of antibodies against the Epstein–Barr nuclear antigen (EBNA) complex, and the date of symptom onset for patients with MS was ...

MS patients start to have increased titers of EBV EBNA-1 antibodies years before MS onset. EBV seroconversion and rising titers of EBNA-1 predict MS onset. Finally EBNA-1 antibodies correlate with ...

In a recent study published in the journal PLOS Pathogens, researchers investigated humoral and cell-mediated immune responses to Epstein-Barr virus (EBV) in multiple sclerosis (MS) patients, post ...