T cell-based immunotherapies, including CAR-T cell therapies, have significantly advanced treatment options for lymphomas ...

Endocannabinoids in the brain play a key role in food intake and energy use. Modulating the action of these molecules could ...

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, ...

There remains an art as much as a science to the use of these drugs. The science behind ACE inhibitor use is well accepted, the art, however, is a work in progress, with many subtleties to use ...

Researchers discovered a vulnerability in viral enzymes that could lead to novel treatments for diseases as diverse as COVID-19 and Ebola -- while also minimizing side effects and reducing the odds of ...

University of Virginia School of Medicine researchers have discovered how long-term treatment of high blood pressure with ...

Endocannabinoids in the brain play a key role in food intake and energy use. Modulating the action of these molecules could help fight obesity, say researchers.

A study in mice offers evidence that inhibiting EZH2 can enhance lymphoma immunogenicity and overcome CAR-T cell therapy resistance.

A study from the University of Michigan Health Rogel Cancer Center may have—at last—cracked the cold case of immunotherapy ...

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, ...

An enzyme called EZH2 has an unexpected role ... even with androgen receptor inhibitors present. PKCλ/ι normally limits EZH2’s activity. However, in PKCλ/ι-deficient cells treated with ...