Until then, our drug discovery efforts had concentrated on the synthesis of gastrointestinal ... as we isolated and characterized these new enzyme inhibitors. However, our synthetic expertise ...

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers are commonly used to treat hypertension and/or a range of progressive end-organ diseases. The success of each of these ...

Influencing their activity can control their rates of reaction. Different chemicals can influence enzyme activity. Inhibitors can be used to stop an enzyme from binding to its substrate.

and inhibiting this enzyme has been found to benefit lymphoma patients even when they have non-mutant EZH2. An EZH2 inhibitor called tazemetostat was approved by the FDA in 2020 for use in ...

A MedUni Vienna study has identified a new approach to the drug treatment of metabolic liver diseases. In an experimental ...

Researchers from the University of Washington are developing new antibiotics targeting bacterial methionyl-tRNA synthetase (MetRS). This enzyme is responsible for charging tRNA(met) with methionine ...