Mechanisms of action Ezetimibe's inhibition of cholesterol absorption results in depletion of the cholesterol in chylomicrons, which in turn leads to diminished hepatic cholesterol and ...

Ezetimibe reduces LDL cholesterol levels, and niacin raises HDL cholesterol levels; however, no previous studies have described the use of these two drugs in combination. Jelesoff and colleagues ...

FH is a genetic condition of very high cholesterol levels that presents a high risk for coronary artery disease.

Ezetimibe is a nonstatin low-density lipoprotein cholesterol-lowering small molecule drug. Ezetimibe is the only currently FDA-approved approved member of the of intestinal cholesterol reuptake ...

It requires great deal of optimism to draw therapy-relevant conclusions from the results of IMPROVE-IT, the key trial addressing a potential benefit of the addition of ezetimibe to simvastatin ...