锐正基因自主开发的ART002是一款以LNP为载体的体内基因编辑新药，旨在通过单次用药，精准编辑LDL-C调控基因PCSK9，以达到持久降低LDL-C水平、降低心血管疾病发病风险的目标。

E3-ubiquitin ligase inducible degrader of the LDL receptor has a similar function, but its role in familial hypercholesterolemia (FH) is unknown.

全球研究显示，早期识别和治疗可以使FH患者的胆固醇水平与普通人群相当。荷兰一项为期20年的研究也显示，若确诊FH的儿童进行早期治疗，可显著降低胆固醇水平，并比受影响的父母更有效地预防心血管疾病。

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients ...

These variations reflect differences in reimbursement policies for Lp apheresis rather than differences in the prevalence of drug-refractory familial hypercholesterolemia (FH), the main indication ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this journey through a disease state ...

Upon successful completion of this educational activity, participants should be able to assess the latest understanding regarding homozygous and heterozygous FH and options for management.

is a rare genetic disorder and most severe form of Familial Hypercholesterolemia (FH), characterized by reduced hepatic clearance and resultant markedly elevated LDL-C leading to premature ...

The study also uses sequencing data to screen participants for medically actionable genetic conditions, such as familial hypercholesterolemia (FH), hereditary breast and ovarian cancer syndrome ...

February is Heart Health Month, a time dedicated to raising awareness about cardiovascular health and the risks associated ...

DEAR DR. ROACH: I am a 69-year-old woman who was diagnosed with familial hypercholesterolemia (FH). I used statins for over a decade but developed vulvar lichen sclerosus (LS), which only went ...

For the freshest news, join The Borneo Post's Telegram Channel and The Borneo Post on Newswav. Previous ArticleSarawak’s third one-stop early intervention centre to open in Miri this June ...