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靶向 FXR 治疗代谢性疾病的关键发现:SRC1 结合机制与转录调控新解
为探究 FXR 转录调控机制,研究人员研究 FXR-RXR α-DNA 与 SRC1 相互作用,揭示关键机制,助力药物研发。 一、研究背景:探寻 FXR 调控密码,解锁代谢疾病治疗新希望 在生命的微观世界里,肝脏就像一座精密运转的化工厂,维持着身体的代谢平衡。然而,近年来 ...
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