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FAPI 放射性药物剂量优化:提升肿瘤诊疗效能的关键突破
在检测技术上,使用了放射性标记技术,将 DOTA.SA.FAPI 等五种 FAPI 配体用镓 - 68(68Ga)标记,并通过反相高效液相色谱(RP-HPLC)和放射性薄层色谱(radio-TLC)进行质量控制。利用 PET/CT 扫描获取荷瘤小鼠的影像学数据,同时采用 RNA 提取、实时定量 PCR(qPCR ...
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