Additionally, FcRn’s ability to affect the antigen presentation of IgG-containing immune complexes to T cells is being increasingly recognized. 10 Therefore, by either or both mechanisms ...

Based on TR-FRET technology and the competitive binding mechanism of human IgG antibodies to FcRn, ACROBiosystems proudly presents the new product: Human FcRn Binding Kit (TR-FRET) (Cat. No. FRT-01).

This FcRn inhibitor is built on blocking the maintaining function of harmful IgG autoantibodies in circulation, which cause a severe immune response in this and other autoimmune disorders.

UCB has the positive result it was hoping for in its phase 3 trial of anti-neonatal FC receptor (FcRn) antibody rozanolixizumab for autoimmune disease generalised myasthenia gravis (gMG), setting ...