"In many patients, the aortic root is the canary in the coal mine, the first area of the aorta ... who directs Johns Hopkins' research on Marfan syndrome, a genetic disorder similar to Loeys ...
The standard treatment for the connective tissue disorder Marfan's syndrome (MFS) is β-blockade, aimed at reducing aortic wall stress. Angiotensin II type 1 and 2 receptors (AT 1 and AT 2 ...