“Our test is more than 95% concordant with reference labs' assessment by FISH,” says Steve Shak, chief medical officer at Genomic Health. HER2 is one of 21 genes included in ...

Future Oncol. 2015;11(7):1023-1026. Tumor-negative breast cancers misclassified as HER2 negative by IHC (0 or 1+) could therefore be reclassified by FISH, with a remarkable impact on medical ...

For patients with an IHC score of 2+, a FISH test can delineate between HER2-positive and HER2-low status. An IHC score of 3+ is considered HER2 positive An IHC score of 2+ is considered HER2 ...

The analysis was performed on independent study sets of HER2-positive and negative/low breast cancers, already analyzed by central immunohistochemistry (IHC) and FISH testing. Phospho-HER2 and ...