A number of cell surface and nuclear receptors mediate their actions via dimerization. While this has been well established, the dimerization of G-protein coupled receptors (GPCRs) (that ...

The crystal structure of a second G protein–coupled receptor sheds light on these key ... The availability of the new β2AR structures is a great step forward for the field of GPCR biology ...

They also realized that the β-adrenergic receptor was one of many in a whole family of receptors that function in the same way. This family is now known as G-protein-coupled receptors, and the studies ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

NIH-funded research team engineers new drug targeting pain sensation pathway: Bethesda, Maryland Friday, March 7, 2025, 17:00 Hrs [IST] A research team funded by the National Inst ...

and Osnabrück University successfully designed a new family of protein-based antagonists that selectively block the G-CSFR receptor, which is linked to the emergence of several blood cancers ...