Direct evidence for GPCR heterodimerization came from studies with non-functional GABA B receptors that dimerize to generate a functional receptor. Recent studies have also provided direct ...

These sleeping pills work on the GABA receptors in the brain, which help control our level of alertness or relaxation. The selective GABA medications target only a certain type of GABA receptor ...

to specifically target the α5 subunit of GABA-A receptors in Ts65Dn mice, a classical animal model of DS. They found that the drug had no convulsant effects and did not promote any side effects ...

This is the first study to show a clear benefit of GLP-1 receptor agonists on kidney failure or end-stage kidney disease, suggesting they have a key role in kidney-protective and heart-protective ...

Attachment to the specific binding site enhances the affinity of GABA for its receptor site on the same receptor complex. The pharmacodynamic consequences of benzodiazepine agonist actions include ...