The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...
Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...
Scientists reveal how cancer cells manipulate RNA splicing, increasing tumor growth. A new study introduces antisense ...
Researchers have discovered that cancer cells suppress 'poison exons' -- genetic elements that act as an off switch for protein production -- in a key gene called TRA2 , promoting tumor growth. By ...
Breakthrough discovery in cancer research! Scientists uncover a simple genetic strategy to combat aggressive cancers. Learn ...
A University of Alberta research team has taken the first step toward proving its innovative gene therapy can successfully ...
Gleevec response in GIST varies by mutational profile, with KIT-exon-11 mutation linked to better outcomes, emphasizing ...
A study reveals how cancer disrupts RNA splicing and presents a potential therapy using antisense oligonucleotides to target ...
“The DMD treatment landscape is evolving with the emergence of novel therapies such as exon-skipping and gene therapies,’ said Asiyah Nawab, Healthcare Analyst at GlobalData ...