Janelia and Allen Institute scientists identified different cell types in the motor cortex based on gene expression patterns. These cell types are represented as colored "islands" below the brain.

The algorithm can also accurately predict the effect of mutations on gene expression even for very low-affinity binding sites—regions in the genome where transcription factors bind to DNA, but do so ...

How Is Gene Expression Regulated? The amounts and types of mRNA molecules in a cell reflect the function of that cell. In fact, thousands of transcripts are produced every second in every cell.

Gene expression profile of 1821 reference B-ALL cases (circles) and 76 B-ALL cases from this study (triangles) shown in a two-dimensional Stochastic Neighbor Embedding (tSNE) plot. Each symbol ...