Mayo Clinic's Precision Mouse Engineering Core in Minnesota can construct gene-targeted vectors for mice to assist researchers.

Gene transfer vectors provide investigators important research tools in studies ... In support of the research community, we have generated a large database of all the vectors produced by the VDL ...

Mayo Clinic's Precision Mouse Engineering Core in Minnesota makes embryonic stem (ES) cell-based gene-targeted mice available to researchers.

Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...

Based on this, we have developed a new approach to enhance the efficiency of rAAV-mediated gene expression. This approach uses co-infection with a transgene-containing vector and a second vector ...