Most cell surface proteins, such as growth factor receptors, are N-glycosylated. Biosynthesis of N-linked glycans is initiated in the lumen of the endoplasmic reticulum (ER) with the transfer of a ...

Addition of fucose to a cell-surface glycoprotein receptor demonstrates the power of glycan engineering to direct homing of adult stem cells to a tissue of choice. Stem cells hold great promise ...

A study published in PNAS reveals how a bacterial pathogen coordinates N-acetylneuraminic acid (Neu5Ac) metabolism at the ...

A study reveals how Salmonella enterica leverages a small RNA, ManS, to regulate Neu5Ac metabolism and adapt to the host ...

Influenza viruses attach to cells with a surface viral protein called hemagglutinin (HA). The HA latches on to sugar (glycan) molecule receptors on cells to cause infection. Avian (bird ...

E-602 enzymatically degrades sialoglycans—immunosuppressive cell surface sugars that protect ... “Palleon’s glycan editing therapeutic has the potential to significantly improve treatment ...

Influenza viruses attach to cells with a surface viral protein called hemagglutinin (HA). The HA latches on to sugar (glycan) molecule receptors on cells to cause infection. Avian (bird ...

The HA binds to glycan molecule (sialic acid) receptors on cells to cause infection ... introduced the genetic mutations only into the HA surface protein and did not create or conduct experiments ...