Tophaceous gout is a severe form of gout. It results when uric acid crystals form, leading to growths called tophi around the ...

The previous paragraphs described certain gout scenarios where a faster crystal clearance may be beneficial ... the disappearance of acute attacks and tophi – which may be considered as the ...

Gout tophi totally disappeared and renal function ... caused by the deposition of calcium pyrophosphate dihydrate crystals in cartilage and fibrocartilage. It can present as acute synovitis ...

The discovery of the role played by interleukin (IL)-1 in the pathogenesis of crystal-induced inflammation has opened a new avenue for the management of acute gout. In a landmark paper, Martinon ...

Tophi are a symptom of gout. They are large, hardened masses of uric acid crystals within and around the joints. These masses can cause pain, joint deformity, and limited range of motion.

Gout is a prevalent metabolic disorder characterized by urate crystal accumulation in joints, leading to acute arthritis and tophi formation. Despite advancements in management, the incidence and ...

These crystals lead to arthritis and inflammation. A rare, severe, and chronic form of gout that is difficult to treat is called refractory gout. Chronic arthritis, redness tophi (lumps that develop ...