Her general practitioner diagnosed gouty arthritis because of a high serum uric-acid level (600 µmol/l; normal range 270–380 µmol/l) coexistent with tophi in her hands, and initiated ...

Methods 30 patients with gout with (19 or 63.3%) or without (11 or 36.7%) previous arthritis of the wrist or hand were studied. Diagnosis was made on the basis of the ACR preliminary criteria (all ...

Tophi are a collection of uric acid crystals ... However, not all people with high uric acid levels will develop gout. Hand ...

The urate deposits are incriminated in the inflammatory process; however, their infection is exceptional. We report the observation of an infected gouty tophus of the pinky and the wrist of a ...

According to experts, tophi can form in any of the following body parts: Swelling in joints due to high uric acid is caused by gout – as excess uric acid in the blood forms crystals that deposit ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

We therefore set up a prospective observational DECT study to investigate the regression of tophi after refractory gout patients were exposed to pegloticase ... Patients underwent DECT examination of ...

The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

A young adult patient with gout was incidentally found to have a large mass on the right lumbar spine and sacrum during an abdominal CT scan. A subsequent dual-energy CT (DECT) scan confirmed this ...

The urate deposits are incriminated in the inflammatory process; however, their infection is exceptional. We report the observation of an infected gouty tophus of the pinky and the wrist of a ...

This process of NETosis is critical for understanding tophaceous gout, since tophi are composed of NETs and densely packed MSU crystals. Purine metabolism in apes and humans is fundamentally different ...