为解决静止免疫细胞基因编辑效率低及研究 HIV 感染机制难题，研究人员用 CRISPR-Cas9 编辑体外扁桃体培养的 CD4 + T 细胞，发现能高效敲除基因且不影响细胞功能，对研究 HIV 发病机制和免疫细胞相互作用意义重大。 精准剖析 CD4 + T 细胞与 HIV 病理机制的新突破 在 ...

Between 2016 and 2018, Dr He modified the genes of embryos belonging to eight couples in which only the father was HIV ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas ... is the only reported cure of HIV-1. Here, authors describe an autologous HSC transplant therapy with cells engineered for multilayered ...

Her co-development of CRISPR-Cas9 – a genome engineering technology that allows researchers to edit DNA ... As a UCSF resident, Sandra practiced at Priscilla Chan and Mark Zuckerberg San Francisco ...

HIV and hepatitis B that persist in their hosts. He studies the ways in which these viruses evade the immune system and potential therapies for these infections. Dr. Jerome and his colleagues are ...