A recent study has identified a triple stranded HIV cDNA intermediate of reverse ... In the host cell nucleus, the viral enzyme integrase directs integration of the viral cDNA into genomic ...

Dolutegravir is an HIV integrase strand transfer inhibitor ... but this is not an indication of worsening renal function. Dolutegravir is not an inducer or inhibitor of CYP450 or uridine ...

The four main classes, which most people are treated with, target one of three viral proteins which control HIV’s lifecycle: reverse transcriptase, integrase and protease. Historically, most people ...

The litigation extends back to 2018, when ViiV – a joint venture majority owned by GlaxoSmithKline alongside Pfizer and Shionogi – accused Gilead of infringing its patents on HIV integrase ...