介绍 HIV-1导致艾滋病。作为一个逆转录病毒，HIV-1在病毒粒子中携带的是RNA基因组，是在感染新细胞时将RNA基因组转化为病毒DNA，并整合到宿主染色体中形成原病毒，进而依赖宿主机制来表达原病毒基因组。宿主RNA聚合酶II （Pol II）转录原病毒生成病毒RNA ...

A recent study has identified a triple stranded HIV cDNA intermediate of reverse transcription, or a ‘central DNA flap,’ as a ... two copies of genomic viral RNA in the form of a dimer.

HIV is a virus. Viruses are microscopic germs that are unable to multiply (replicate) by themselves. Instead, they need to find and infect a cell that will act as a host in which new viruses can be ...

A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible ...

The full–length chimeric molecules constructed from plasma–derived HIV–1 RNA and proviral DNA–derived LTRs were tested for infectivity by transfection into human dermal fibroblast cells ...

The naked-DNA vaccine is complete ... Note: Although the genetic material of HIV is RNA, the procedure for making the vaccine is similar.

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs, and an intricate frameshift site structure that regulate viral protein synthesis. These findings highlight ...

After the HIV virus releases its genetic material into a host cell, reverse transcriptase converts the viral RNA into DNA, a process known as ‘reverse transcription’. NRTIs disrupt the construction of ...

Cytosine can also be isolated from DNA or RNA through enzymatic digestion and chromatographic purification techniques ... Lamivudine (3TC): A cytosine analog used as an antiviral agent in the ...