Of note, the vector particles, used in our experiments, were produced in the absence of all HIV-1 accessory proteins (vif, vpr, vpu, and nef), indicating that these proteins do not appear to be ...

HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.

The culprit is an HIV-1 accessory protein known as viral protein R (Vpr). The findings reported by the researchers answer some of the questions as to why patients receiving successful treatment for ...