HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.

Of note, the vector particles, used in our experiments, were produced in the absence of all HIV-1 accessory proteins (vif, vpr, vpu, and nef), indicating that these proteins do not appear to be ...

The culprit is an HIV-1 accessory protein known as viral protein R (Vpr). The findings reported by the researchers answer some of the questions as to why patients receiving successful treatment for ...

J. Immunol., 196: 1832-1841 (2016). 5.Hagiwara K, Ishii H, Murakami T, Takeshima SN, Chutiwitoonchai N, Kodama EN, Kawaji K, Kondoh Y, Honda K, Osada H, Tsunetsugu-Yokota Y, Suzuki M & Aida Y: ...