clinically severe hemoglobin SS disease (n = 184) and other sickling hemoglobinopathies (a total of 116 patients with the heterozygously inherited, generally less-severe SC or SD disease ...

"However, the cells can sickle, and so many clinical manifestations are the same as hemoglobin SS. To date, there is no effective disease-modifying treatment available for hemoglobin SC patients." ...

The tested population included 73 patients with hemoglobin SS, the most serious form of sickle cell disease, 20 patients with hemoglobin SC, and 5 patients with other blood dyscrasias. The sample ...

The knowledge and awareness of genotype must start from the parents, adding that this understanding would aid the transfer of ...

When we compared patients with hemoglobin SS with control children matched for ... status), we found that children with sickle cell disease again scored lower than healthy children ( Table 4).

YolTech Therapeutics, a clinical-stage gene editing company dedicated to delivering lifelong cures, announced the initiation of a clinical trial for YOLT-204 , an investigational ...