热休克蛋白 90（Hsp90）抑制剂在抗癌研究中潜力大但挑战多，本文进行了全面综述。 热休克蛋白 90（Hsp90）抑制剂作为抗癌药物的研究进展 在生命科学和健康医学领域，热休克蛋白 90（Heat Shock Protein 90，Hsp90）是一类备受瞩目的分子伴侣。它高度保守，在众多 ...

Heat-shock protein 90 (Hsp90) inhibitor downregulates c-Myc expression and upregulates the expression of tumor repressor proteins such as p53 and pRB, inhibiting the G1/S transition and causing G2 ...

We determined the structure and function of Heat Shock Protein 90 (Hsp90), a molecular chaperone which is critical for the growth and survival of cancer cells. We worked with partners to discover the ...

Pembrolizumab and XL888 in advanced CRC showed manageable safety, though limited responses and potential immunomodulatory ...