为探究鼻咽癌顺铂（DDP）化疗耐药机制，研究人员聚焦 HAX-1、IGF2BP1 等，发现二者正反馈回路阻断自噬通量，或可预测耐药风险。 在癌症治疗的战场上，化疗是对抗肿瘤的重要武器，其中顺铂（DDP）更是在多种实体肿瘤治疗中发挥着关键作用，像鼻咽癌（NPC ...

The project, titled "Treating Lung and Colorectal Carcinomas by Targeting IGFBP1" will study the effects of an IGF2BP1 inhibitor discovered by Professor Yisraeli and his team, building upon ...

IGF2BP1 is a protein that binds to RNA and is usually active before birth, but it becomes active again in many types of cancers. In patients with lung adenocarcinoma, those with high levels of ...