Cancer cells are the exception to the Hayflick ... This excerpt from Why We Die: The New Science of Ageing and the Quest for Immortality by Venki Ramakrishnan has been published with permission ...

The clinical development of conventional cytotoxic anti-cancer agents involves the determination of the optimal dose and schedule of the novel agent, based on the assessment of drug-related ...

We expressed this mutant (DN-hTERT) ectopically in human immortalized cells and cancer cells to assess the biochemical and physiological effects of telomerase inhibition on cellular immortality ...