Selective modulation of the apoptotic machinery has been the goal of oncology developers for more than two decades. The field continues to face special challenges. Many of the targets are ...

analysis of caspase-8 and -9 protein levels were conducted in an attempt to determine what apoptotic induction pathway (intrinsic vs extrinsic) was responsible for early-onset apoptosis (Figures ...

Apoptosis is a highly regulated and critical homeostatic process in multicellular organisms. Aberrations in this form of programmed cell death have been implicated in several pathological conditions ...

3. What is apoptosis? What is its function in cell cycle regulation? Describe the difference between and intrinsic apoptotic pathway and an extrinsic apoptotic pathway. What might happen if a cell is ...