In the case of the enzyme, isocitrate dehydrogenase, the kinetic alterations ... the concentration of an allosteric activator could go from zero to 1μM in 0.1 second or from 1μM to zero in ...

Mutant isocitrate dehydrogenase (mIDH ... and STAT signal transducer and activator of transcription. In short, the study by Wu and colleagues highlights the role of tumor cell–autonomous ...