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生物通
15 天
脊髓损伤后,脂多糖激活小胶质细胞的 “秘密行动”:解锁神经可塑 ...
研究人员为探究脊髓损伤(SCI)后小胶质细胞与可塑性的关系,用单细胞 RNA 测序研究,发现小胶质细胞状态随时间和 LPS 注射改变,为 SCI 治疗提供新思路。 单细胞 RNA 测序(single-cell RNA sequencing,scRNAseq) :通过该技术对不同阶段(亚急性期和慢性期)、不同处理(注射 LPS ...
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