AML originates from a rare population of cells, termed leukemic stem cells (LSCs) or leukemia-initiating cells, which are capable of self-renewal, proliferation and differentiation into malignant ...

The central aim of Professor Kamil Kranc's group is to discover the key mechanisms regulating leukaemic stem cell (LSC) biology and harness this knowledge to selectively eradicate LSCs, thus ...

This unfavorable prognosis may be due to the presence of so-called ''dormant'' or ''quiescent'' leukemic stem cells (LSCs), which evade chemotherapy. Often invisible, these cells can ''wake up ...