For example, apoC-II activates the enzyme lipoprotein lipase (LPL), which removes TG from lipoprotein particles such as chylomicrons and VLDL. Each lipoprotein class (chylomicrons, VLDL ...

In FCS, mutations in the lipoprotein lipase gene lead to an accumulation of chylomicrons in plasma resulting ... were randomly assigned to receive plozasiran (25mg or 50mg) or placebo via subcutaneous ...