Right now, nonhuman primate models are only attainable following temporary changes, like adding the HBV entry receptor, a human protein called NTCP, to liver cells with the help of viral vectors.

Additionally, the hepatitis D virus (HDV), an enveloped RNA satellite virus that uses HBV surface proteins in HBV/HDV co-infection, enhances the severity of liver disease. NTCP (SLC10A1), involved ...

Axiomer™ ADAR-mediated RNA editing pipeline advancing across liver and CNS programs, with CTA filing on track for Q2 2025 for lead program AX-0810 targeting NTCP for Cholestatic diseases.

Axiomer ADAR-mediated RNA editing pipeline advancing across liver and CNS programs, with CTA filing on track for Q2 2025 for lead program AX-0810 targeting NTCP for Cholestatic diseases Company ...