Simulation of DNA organized into two globules by loop extrusion. The figure-8 structure indicates the extrusion complex ... “Now that we have these experiments, we can claim a causal effect, which in ...

In TET deficient mice, DNA forms strange structures called G-quadruplexes (G4s) and R-loops that may drive cancer development, a December 22 study in Nature Immunology suggests. The paper “is a great ...