Lymph node metastasis (LNM) is a critical factor in determining the prognosis and treatment strategies for colorectal cancer, particularly in early-stage cases such as T1 colorectal cancer.

Researchers have developed lab-generated lymph node–like organoids that, when transplanted into mice in place of lymph nodes that have been removed, drain fluid and connect to the animals’ original ...

Looking at human lung tumor samples from patients with metastatic breast cancer, the scientists noted a similar translational program as in mice and an elevated expression of the NMDA receptor ...

Oriol Casanovas, Douglas Hanahan and colleagues studied the response to VEGFA–VEGFR2 pathway inhibition of pancreatic neuroendocrine cancer in the RIP1-Tag2 mouse model and glioblastoma ...