Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells' digestive systems by getting rid of unwanted materials. Now in a groundbreaking ...

MLRO is a unique organelle formed by the fusion of a mitochondrion and a lysosome, a cellular "garbage disposal" unit. This hybrid organelle appears to be an alternative way to break down damaged ...

Once cardiac myocytes release the mitochondria-containing EV, resident cardiac macrophages and other cells in the heart internalize the vesicles to degrade them through their lysosomes. The EV do not ...