为探究 lncRNA-MALAT1 在三阴性乳腺癌（TNBC）中的作用及机制，研究发现其可通过 MALAT1/miR-106a-5p/REEP5 轴促进 TNBC 进展，为 TNBC 诊疗提供新思路。 在癌症的世界里，乳腺癌无疑是一个 “狠角色”，而三阴性乳腺癌（TNBC）更是其中的 “佼佼者”。TNBC 是指雌激素受体 ...

Much of our early work focused on the MALAT1 locus, which is over-expressed in many human cancers and produces a long nuclear-retained noncoding RNA as well as a tRNA-like small RNA known as mascRNA, ...