为探究挥发性有机化合物（VOCs）对 MDA 5-ILD 的诊断价值，研究发现其可提升诊断效能并评估病情。 间质性肺疾病（ILDs）是一类以肺纤维化、炎症和肺组织退变为特征的肺部疾病。抗黑素瘤分化相关基因 5 阳性皮肌炎相关间质性肺疾病（MDA 5-ILD）作为其中的一个 ...

为探究 JAK 抑制剂对儿童抗 MDA5 阳性幼年皮肌炎（JDM）伴 ILD 的疗效，国外研究人员开展相关研究，发现托法替尼治疗有效且安全，为治疗提供新方向。 一、研究背景 在医学领域，幼年皮肌炎（Juvenile dermatomyositis，JDM）是一种较为罕见的自身免疫性疾病 ...

The rare but life-threatening illness currently surging among the residents of Yorkshire is known as Anti-MDA5 positive ...

Now, a group at TMDU has created a murine model for a disease known as "anti-MDA5 antibody-positive dermatomyositis." The use of this model has allowed them to identify components of the immune ...