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9 天
非洲猪瘟病毒 pS183L 蛋白调控 MDA5 寡聚化的机制及其对防控的意义
研究人员开展了 ASFV 的 pS183L 蛋白对 RLR 信号通路影响的研究。结果发现 pS183L 抑制 MDA5 寡聚化,干扰 IFN-β 信号通路。该研究为 ASF 防控提供新靶点,意义重大。 非洲猪瘟(ASF)自 1921 年在肯尼亚被发现以来,像一场可怕的瘟疫,在非洲、欧洲、亚洲等地不断蔓延。
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