Major histocompatibility complex (MHC) class I presentation of peptides to T cell receptors (TCR) on T lymphocytes is the key in the immune response. Because of their unique specificity, MHC-peptide ...

T cells use the T cell antigen-receptor (TCR) to recognize their antigens, which are often in the form of peptides bound to major histocompatibility complex molecules (MHC), also called HLA (human ...

Recently developed major histocompatibility complex (MHC) multimer technologies allow visualization and isolation of antigen-specific T cells. However, functional analysis and in vivo transfer of ...

Many attempts at cancer immunotherapy have been conducted; however, apart from melanoma, in which impressive clinical responses have been noted in a small minority of patients, the overall results ...

Some of these antigenic peptide fragments, which are between eight and 12 residues in length, are presented on the cell surface by class I major histocompatibility complex (MHC I) proteins.

While it's known that major histocompatibility complex class I (MHC-I ... protein building blocks found within peptide antigens displayed on the surface of MHC-I molecules. Next, investigators ...