为解决克罗恩病（CD）肛周病变治疗难题，研究人员开展间充质干细胞（MSC）疗法治疗肛周瘘管型 CD 的研究。结果显示 MSC 疗法有效，6 个月达最佳疗效，且脂肪来源干细胞（ASCs）和骨髓来源干细胞（BMSCs）疗效无差异，为 CD 治疗提供新方向。

近日，解放军总医院第五医学中心、国家感染性疾病临床医学研究中心王福生院士团队在权威期刊Stem Cell Research & ...

2012年，美国FDA拒绝了Osiris的骨髓来源药物Prochymal的上市申请。其宣称的干细胞修复机制与其临床数据脱节，且缺乏可验证的效力测定方法支持。这一结论在Osiris的2012年SEC文件与美国FDA 2017年细胞治疗指南中均有迹可循。这一失败揭示了关键问题：缺乏有效的效力测定、未见明确的作用机制以及未证实MSC在体内发挥"干细胞"的分化能力。

在骨科领域，骨折不愈合是一个令人头疼的难题。想象一下，骨折患者本应在一段时间后康复，可有些患者的骨折部位却迟迟无法愈合，需要反复治疗，这不仅让患者承受身体上的痛苦，还严重降低了他们的生活质量。据统计，近 5 - 10% 的骨折会出现延迟愈合或不愈合的情况。目前，虽然有一些治疗方法，比如物理刺激疗法、lncRNA 和 miRNA ...

Aged individuals and astronauts experience bone loss despite rigorous physical activity. Bone mechanoresponse is in-part ...

More than 55,000 studies have been published on MSC cell biology and their possible therapeutic applications. MSC therapies involve isolating and growing cells and manipulating them if required ...

December 2024, immediately following the approval of the world's first mesenchymal stromal cells clinical trial, the U.S. FDA ...

Postgraduate Certificate in Stem Cells and Regeneration Postgraduate Diploma in Stem Cells and Regeneration MSc in Stem Cells and Regeneration. You will typically need an upper second-class honours ...

Our MSc Cell Biology course will enable you to consider the most exciting current problems in the field under the guidance of leading experts in cell biology. Rather than attending traditional ...

Take a research-focused master's course where you will learn through seminars, workshops, small group tutorials and research placements. Your research placement will be in the laboratory of a leading ...