Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components ...

Donini is an inventor of Soligenix’s Innate Defense Regulator (IDR) technology, which offers broad applicability across inflammatory ... macrophages nor bias their development along the M1-M2 ...

Macrophages serve as the Swiss army knives of the innate immune system, switching between phenotypes to perform different functions in response to the surrounding environment. One of their key ...

The immune cells were at a 7 times higher ratio in lung samples from men than women, and may explain sex differences between ...

Researchers focused particularly on the role of M1 and M2 macrophages in the ... cells and weaken the androgen response. We ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

The study identified cell types linked to the development of epithelial cells and the immune response ... inflammatory M2 macrophages were higher in PCP. Accordingly, a higher ratio of M1 and ...