The future will see intensified efforts to map signal transduction pathways and link them to disease. In this regard, Isis Pharmaceuticals employs an interesting method for mapping pathways using ...

They affect similar processes but, paradoxically, their signaling pathways act nonredundantly. Hormone signals are integrated at the gene-network level rather than by cross-talk during signal ...

Jennifer Klomp and colleagues 7 used advanced mass-spectrometry techniques to map the ERK ... on ERK signaling. Together, these studies uncover novel compensatory pathways that may be involved ...