The blood–brain barrier is the biggest challenge to the development of drugs that target the CNS. Most capillary beds leak plasma contents between and across endothelial cells by way of window-like ...

Voyager Therapeutics focuses on developing blood-brain-barrier (BBB) crossing treatments ... that the global neuroscience market, including drug therapies, non-drug therapies and diagnostics ...

Scientists from the University of Liverpool and their global collaborators have highlighted the most effective treatments for ...

Dendrimers are of great interest for drug delivery because of their ability to cross cell membranes ... production of this manuscript. The blood–brain barrier (BBB) is a significant obstacle ...

The new technique, called the blood-brain barrier-crossing conjugate (BCC) system, "breaks this barrier," Dong said, allowing medications "to reach the central nervous system safely and efficiently." ...

Scientists from the University of Liverpool, and their global collaborators have highlighted the most effective treatments ...

Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.

Dr. Chen is developing a new delivery system which is designed to help cancer drugs cross the blood-brain barrier.

Researchers and physicians at Sunnybrook Health Sciences Centre and The Hospital for Sick Children (SickKids) are the first ...

Penn Engineers have modified lipid nanoparticles (LNPs) — the revolutionary technology behind the COVID-19 mRNA vaccines — to not only cross the blood-brain barrier (BBB) but also to target specific ...