Metformin, a biguanide ... of the peroxisome proliferator-activated receptor-γ (PPARγ), which promotes adipocyte differentiation and improves insulin sensitivity. The principal liabilities ...

The degree of insulin resistance (IR) correlates with disease severity and is associated with reduced exercise capacity. In this proof of concept study, we have examined the effect of metformin on ...

Previous studies have suggested that metformin and GLP-1 receptor agonists may reduce ... SGLT2 inhibitors, and insulin, but none of these showed associations with a reduction in asthma attacks.

The American Diabetes Association/European Association for the Study of Diabetes consensus statement, which includes the use of GLP-1 receptor agonists as a secondary option to add to metformin ...

They found that metformin was associated with a 30% reduction in asthma attacks, and glucagon-like peptide-1 receptor agonists ... and downregulation of insulin-like growth factor 1, all of ...